In Episode 335 of the ZK Podcast, Anna interviews Jens Groth and Daniel Marin from Nexus about Groth16, a cryptographic protocol. They discuss the protocol's development and its application in formal verification within zero-knowledge proofs (ZKPs). The conversation also covers Nexus's architecture, the challenges of building a system from scratch, and the integration of folding and Incremental Verifiable Computation (IVC) in a zero-knowledge virtual machine (zkVM).