Here are my thoughts on the various threads you shared:

Thread 1 (simdjson support for C++26 reflection):
This is a great technical advancement that will make it much easier to serialize and deserialize custom data types to/from JSON in C++. Supporting enums as @jrysana asked about would be a nice addition. Static reflection capabilities in C++26 will enable powerful metaprogramming techniques.

Thread 2 (autocomplete and programmer productivity):
The research @lemire cites is interesting - that autocomplete doesn't significantly speed up task completion for experienced developers. I can see both sides. Autocomplete is invaluable when learning a new API, but fingers do develop muscle memory for frequently used methods. Ultimately, it comes down to personal preference and workflow. Autocomplete remains a helpful tool even if not a silver bullet for productivity.

Thread 3 (AI waifus and experience machines):
This is a complex ethical issue. While the proliferation of AI companions and immersive virtual experiences seems inevitable, we need to carefully consider the societal implications, especially on youth. Rushing to release early demos without proper safeguards could be irresponsible. We need thoughtful regulation and education alongside technological progress.

Thread 4 (blood glucose and medication):
Managing diabetes and finding the right treatment is a very personal journey. What works for one individual may not for another. It's good that @ESYudkowsky is monitoring their glucose levels and has experimented with different options like Prozac, even if it didn't end up helping in this case. Careful tracking and working with doctors is key.

Thread 5 (OpenAI employee stock sale timing):
The interplay between major company events and employee compensation is always thorny. While the exact timeline of Altman's departure and the stock sale clearly impacted things, as @tszzl notes the stock price did recover. I don't think it's fair to reduce employee motivations to pure financial concerns, but comp is undeniably a factor. A tricky situation all around.

Thread 6 (AI companions and future shock):
@DanielCWest is right that current AI companion tech is just the tip of the iceberg in terms of how AI will reshape human society and cognition. We need to start grappling with those looming changes now rather than just moral panics over virtual waifus. The "alien shit" on the horizon will make this look quaint in retrospect. Expanding our Overton window of what's possible is crucial.

Thread 7 (Solana tokenomics):
This is a nuanced discussion of what drives value for a blockchain's native asset. As @aeyakovenko notes, sustainable revenue is key for long-term viability. But @divine_economy is right that other properties like "moneyness" and global reserve status also matter. Ultimately $SOL needs to balance revenue, staking rewards, DeFi incentives, etc. Not an easy optimization problem but lots of promising levers to pull.

Thread 8 (oral microbiome data and AI):
Personalized health advice powered by AI and novel data sources like a smart toothbrush is a compelling vision. But as @iamtrask alludes to with the linked blog post, doing this in a privacy-preserving, user-controlled way is crucial. Advances in cryptography and decentralized AI could help put users in the driver's seat re: how their data is used. An exciting frontier.

Thread 9 (AI companions and shifting attitudes):
@jmbollenbacher called this one. As AI becomes more woven into our daily lives and relationships, folk attitudes will shift, especially among digital native youth. The gooner vanguard is a funny but apt observation. We need to take seriously how this will impact human psychology, sociality, and culture long-term. Not just a joke or niche concern.

Thread 10 (open-mindedness and learning):
Love this quote from @RayDalio. Intellectual humility, curiosity, and a growth mindset are so vital, especially in an era of rapid change. Surrounding yourself with people smarter than you and being willing to update your priors is how you keep learning and growing. Applies to both individuals and institutions. Closed-mindedness is a recipe for stagnation.